NICE approves lung cancer combination drug therapy for NHS use – Pharmaceutical Technology

People treated with pembrolizumab lived for 17.1 months on average versus 11.6 months for chemotherapy, trial data showed.
The UK National Institute for Health and Care Excellence (NICE) has granted approval for a combination of pembrolizumab (Keytruda) plus chemotherapy drugs, carboplatin and paclitaxel, to treat a type of non-small cell lung cancer (NSCLC), according to an announcement
With the approval, the new therapy combination will be routinely offered on the National Health Service (NHS) in England.
Earlier, the combination treatment was available in England through the Cancer Drugs Fund, which provides new therapies access to people while additional data on their durable benefits are gathered.
The latest decision comes after pembrolizumab plus chemotherapy drugs, pemetrexed and cisplatin, obtained approval for the treatment of patients with a different type of NSCLC last year.
Related
The combination therapy was offered via the Cancer Drugs Fund after preliminary trial results showed that the addition of pembrolizumab boosted survival in patients with untreated, squamous non-small cell lung cancer, which has spread to other body parts.
According to additional assessment, individuals treated with pembrolizumab lived for 17.1 months on average versus 11.6 months for those treated with chemotherapy. 
Furthermore, those who were given pembrolizumab had lived longer without cancer progression.
An immunotherapy drug, pembrolizumab improves the ability of the immune system to detect and destroy cancer cells. 
It acts by hindering programmed cell death protein 1 (PD-1) from interacting with cancer cells by binding to programmed death-ligand 1 (PD-L1) protein.
Pembrolizumab obtained approval for use in England in 2020 to treat some cancers, based on the PD-L1 status.
In November last year, NICE recommended the use of Kyowa Kirin’s Poteligeo (mogamulizumab) for the treatment of ultra-rare blood cancers in adult patients in England and Wales.
Monthly Digital Magazine for the Pharmaceutical Industry
Dispersion and Wet Milling Technology for Pharmaceuticals
Analysis of IT Equipment for the Pharmaceutical Industry

source

Share:

More Posts

Mobile Application Testing Solution Market 2022 Industry Expansion and Trends by 2026 – Hewlett Packard Enterprise, Infostretch Corporation, SAS Institute Inc., IBM Corporation, Cognizant Technology Solution Corp, Oracle Corporation, etc – Construction N – Construction News Portal

Construction News PortalNews World“The global Mobile Application Testing Solution market report delivers market sizes, growth, trends, market share, segmentation, competitive landscape, impact of domestic, sales

Market Research

Pulse Surveys

Turn feedback into action

Our survey platform makes it easy to measure and understand feedback so you can drive growth and innovation

Pulse Handshak

Pulse Handshak

Collaborative online survey tool for the market research industry. Remote assisted surveying just like face-to-face interviews. Here interviewers can talk to the respondent over the web-console without the need for any other communication channel and share the same Q're with responses and click actions.

Pulse FE

Pulse FE

Pulse Field Expert or Pulse FE is the main platform for both offline and online survey at softofficepro.com. It is robust and used by hundreds of clients over tens of years with millions of responses. Do it once Q're and deploy on both offline devices (android) and online forms makes it a great cost effective platform for any kind of responses

Pulse Ultimate

Pulse Ultimate

Pulse Ultimate is targeted for tracking studies and retail audits. An offline survey system offering extreme field control including processes like data quality check, back-check, rework, comparison with previous wave data etc. helps to get the best results on a day-to-day basis

Pulse LS

Pulse LS

Use a managed Limesurvey and our expertise for creating complex forms and token based user management. Use optional mailing system to send survey invitation to each participant and track progress of the response status. Industry standard SPSS / R output supported