New Cell Freezing Technology Takes Development Time to 24 Hours – Zenopa

A vital technique for drug discovery is the utilisation of cells in closely packed layers. Cells preserved in this fashion and frozen take up to two weeks to develop before use due to restrictions in existing cryopreservation techniques. Therefore, it takes longer to develop the cells than it does to conduct research with them, rendering the method inefficient.
To address this issue, members from the GibsonGroup in Warwick manufactured a cell-freezing technology in collaboration with Warwick university’s early-stage biotechnology company Cryologyx Ltd.
BioMacromolecules described the development whereby CryoShield macromolecular cryoprotectant technology is utilised to prevent cold stress; this has the ability to seriously impact the functionality of cells that have not been unfrozen properly. This means that cells may be removed from the freezer, defrosted, and employed for research in under a day.
The report stated that “overall, we have demonstrated that cells can be cryopreserved as ‘assay-ready’ monolayers, in a scalable and versatile manner, which will enable the development of new screening technologies, enhance automation, and reduce the experimental burden on researchers.”
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